Open access
Jul 2026
Colon-targeting pH-responsive Bletilla striata polysaccharide coacervate microdroplets for ulcerative colitis therapy via macrophage reprogramming
Ulcerative colitis (UC) is an immune-mediated chronic inflammatory bowel disease that severely impairs patients’ quality of life. Efficient oral colon-targeted delivery systems are urgently needed to improve local therapeutic efficacy while minimizing systemic exposure. Herein, we developed a pH-responsive Eudragit S10...
Qiantao Zhang, L. Chai, Hui Liu et al.
· Journal of Nanobiotechnology · 0 citations