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Xiaotian Pan

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Open access Jul 2026

Deep learning-based classification of colonoscopic images using an attention-enhanced ConvNeXt V2 architecture

Introduction Proper interpretation of the colonoscopic images is important to early detect and diagnose colorectal diseases like polyps and inflammatory bowel diseases. However, the complex visual patterns and high intra-class similarity of such images make the automated classification task challenging. Methods In this work, we propose an attention enhanced deep learning framework using ConvNeXt V2 for robust multi-class classification of colonoscopic images. The proposed method employs a Convolutional Block Attention Module (CBAM) in ConvNeXt V2 architecture to improve the feature representation by emphasizing the diagnostically relevant regions and ignoring the irrelevant background information. We used a balanced dataset of three classes: cecum (normal), polyp and ulcerative colitis with a uniform spatial resolution of 720 × 576 pixels. To improve the generalization of the model, we performed data augmentation for the training. The performance of the proposed model was extensively evaluated using 5-fold stratified cross-validation. Results Experimental results show that the proposed approach achieves a mean classification accuracy of about 95% which is significantly better than the baseline ConvNeXt V2 model which achieved about 90% accuracy. Furthermore, the proposed model achieved a mean precision of 95.1% and an F1-score of 94.9%, which shows a reliable classification of all classes. Moreover, qualitative analysis by attention visualization reveals that the model can focus on clinically relevant areas related to pathological features. Discussion The results demonstrated the effectiveness of modern convolutional architectures with embedded attention mechanisms in improving diagnostic performance in the analysis of colonoscopic images. The proposed framework provides a powerful and efficient tool for automatic classification of colorectal diseases and can assist clinicians for decision making.

Xiaosheng Jin, Lu-Xi Chen, Liwei Xue et al. · 0 citations
Open access Aug 2026

Large-scale neuromorphic modeling of cortical networks on FPGA for investigating anesthetic-induced neural dynamics

Understanding the neural mechanisms underlying general anesthesia remains a significant challenge in neuroscience and clinical practice. Traditional software-based simulations of large-scale brain networks are often constrained by high computational costs and fail to achieve real-time performance. In this paper, we propose a high-performance hardware implementation of large-scale neuromorphic system to investigate anesthetic-induced neural dynamics. The system successfully models a cortical network comprising 10,000 spiking neurons (8,000 excitatory and 2,000 inhibitory) utilizing the biologically plausible Izhikevich neuron model. Deployed on a field-programmable gate array (FPGA), the proposed architecture exploits high parallelism to achieve real-time simulation speeds. By adjusting synaptic weights and network parameters to mimic the pharmacological eects of anesthetic agents, our system can continuously monitor and evaluate state transitions in neural synchronization and firing patterns. The results demonstrate that the hardware-accelerated neuromorphic approach provides an efficient, scalable, and real-time platform for investigating large-scale neural dynamics. Pending future validation against empirical clinical EEG data, this foundational framework paves the way for advanced brain–machine interfaces and closed-loop anesthetic delivery systems.

Chuan-Guang Wang, Xiaotian Pan, Si Chen et al. · 0 citations