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Xiaoxiao Shi

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Review Open access Jul 2026

Application of CRISPR-Cas9-Based Gene Editing Technology in Inherited Liver Diseases

This review systematically elucidates the working principles and technical advantages of the CRISPR-Cas9 system and its derived tools (base editing and prime editing), summarizes recent applications of these technologies in the treatment of hereditary liver diseases, and discusses the prospects and challenges of their clinical translation.

Ran Liu, Shiqi Cong, Yuan Gao et al. · 0 citations