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Author

Xiaoxue Fan

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Jul 2026

ace-miR-3759-y Orchestrates Honeybee Larval Defense against Fungal Infection through Modulating Dual Targets and Oxidative Stress Response.

Chalkbrood disease, caused by Ascosphaera apis, threatens Apis cerana larvae. However, miRNA-mediated antifungal regulation remains poorly defined. Here, we characterized ace-miR-3759-y in A. apis-challenged A. cerana larvae. Stem-loop RT-PCR and Sanger sequencing confirmed its gut expression. Target prediction identif...

He Zang, Haimei Yue, Xiaoxue Fan et al. · 0 citations
Open access Aug 2026

LncRNA6470/ace-miR-750-y axis modulates AcPP2A gene, immune response and survival of eastern honey bee larvae during fungal infection

ABSTRACT Chalkbrood, a destructive larval disease caused by the fungal pathogen Ascosphaera apis, causes substantial losses in apiculture. Although host–pathogen interactions in Apis mellifera larvae infected with A. apis have been investigated, immune defense mechanisms in the Asian honey bee Apis cerana remain unclea...

Xiaoxue Fan, Kaiyao Zhang, Yun Yang et al. · 0 citations

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