Small RNA sequencing identifies T cell-derived tsRNAs as novel biomarkers for diagnosis and clinical assessment of rheumatoid arthritis.
OBJECTIVE The functional role of tRNA-derived small RNAs (tsRNAs) in CD3+ T lymphocytes in rheumatoid arthritis (RA) remains unclear. This study aimed to characterize their expression profile and evaluate their biomarker potential in RA. METHODS Small RNA sequencing of CD3+ T lymphocytes was performed to profile tsRN...