Open access
Aug 2026
Capsimycin derivatives from Streptomyces sp. PH9007 as α‑glucosidase inhibitors and insights into their biosynthetic gene cluster
The increasing number of individuals with diabetes mellitus (DM) highlights the need to develop new diabetes medications. Polycyclic tetramate macrolactams (PTMs), characterized by a macrocyclic lactam containing an integrated tetramic acid ring, constitute an expanding group of extensively dispersed natural comp...
Zhong Wang, Guangling Wu, Jian Pan et al.
· BMC Genomics · 0 citations