Jul 2026
Lipase GehA functions as a positive-feedback amplifier of Cutibacterium acnes-sebum interactions in acne pathogenesis.
It is demonstrated that culturing C. acnes in an artificial sebum system enhances bacterial growth and augments inflammatory, lipogenic, and hyperkeratinization-related responses in keratinocytes, sebocytes, and a Syrian hamster flank organ model.
Yang-Fan Lai, Meng-Jie Fan, Xiaoyao Fan et al.
· Journal of Investigative Der... · 1 citation