Xiaoying Liu

Mitochondrial pearling is controlled by the inner membrane and mediates segregation of the luminal content and membrane scission.

Membrane pearling, the transformation of a smooth tubule into a chain of bead-like swellings connected by narrow membrane tethers, is a widely observed shape change. While it has been well studied for synthetic lipid and unilamellar intracellular membranes, the mechanism underlying the pearling of the peculiar double-m...