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Xiaoyun Chen

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Open access Aug 2026

SET7-mediated methylation of IRF3 at lysine 98 attenuates antiviral innate immunity.

SET7 belongs to the SET domain (SETD) methyltransferase family, which catalyzes the monomethylation of lysine residues in histones and nonhistone proteins. This process can either enhance or suppress gene activation. Interferon regulatory factor 3 (IRF3) is a key transcription factor in the type I interferon (IFN) sign...

Hong-Yan Deng, Xueyi Sun, Huangyuan Zha et al. · 0 citations

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