A machine learning approach to metabolomics identifies putative biomarker candidates and dysregulated pathways for distinguishing gout from asymptomatic hyperuricemia in the Zhuang population
Gout typically develops from hyperuricemia (HUA), but the metabolic alterations driving this transition remain poorly understood, limiting our understanding of disease pathogenesis. To identify stage-specific putative biomarker candidates and to characterize dysregulated metabolic pathways distinguishing gout from HUA....