Open access
Aug 2026
Resveratrol attenuates Cr(VI)-induced ferroptosis through SIRT3 activation in nephrocytes and in vivo.
Hexavalent chromium [Cr(VI)], a widespread environmental toxicant with mutagenic and carcinogenic potential, preferentially accumulates in the kidneys, though its nephrotoxic mechanisms remain incompletely understood. This study demonstrates that Cr(VI) induces ferroptosis, an iron-dependent regulated cell death, in ne...
Muzi Li, Pu Zhang, Zhiyuan Lu et al.
· Ecotoxicology and Environmen... · 0 citations