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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Xin-Chang Zheng

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Open access Aug 2026

IsoAtlas: Visual interpretation of known and novel transcript isoforms using population-scale long-read evidence

Long-read RNA sequencing has revealed extensive transcript diversity, but newly observed isoforms remain difficult to interpret beyond their classification as known or novel. Here, we present IsoAtlas, an interactive multispecies database for visual exploration and population-scale interpretation of transcript isoforms...

Xin-Chang Zheng, F. Sedlazeck · 0 citations
Open access Sep 2026

Isocall enables scalable transcript identification from long-read RNA-sequencing data

Isocall, a scalable and deterministic computational method for jointly calling transcripts from multiple PacBio long-read RNA sequencing samples, converts aligned full-length non-concatemer reads into compact per-sample transcript profiles, merges these profiles across samples, and jointly identifies known and novel tr...

E. Dolzhenko, Megan D. Schertzer, Ryan Gossart et al. · 1 citation
Sep 2026

Bioinformatics for human long-read whole-genome sequencing

This Primer outlines the computational foundations of long-read whole-genome analysis in human genomics, spanning read processing, mapping, de novo assembly, multi-class variant detection, haplotype phasing, repeat analysis and epigenetic profiling, and highlights key analytical trade-offs between mapping-based and ass...

Xin-Chang Zheng, P. Sanio, Rui-Bang Luo et al. · 0 citations
Open access Aug 2026

SALRR: Scalable Analysis of Long-Read RNA-Seq Enables Comprehensive Transcriptome Profiling in Human Brain

An integrated wet-lab and computational platform designed to overcome barriers to population-scale long-read RNA sequencing, providing a scalable, community-ready framework for isoform-resolved transcriptomics in neurodegeneration, aging, and complex brain disease.

C. Kouam, Jackson Mingle, Pilar Álvarez Jerez et al. · 0 citations

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