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Author

Xin-He Wang

2 papers indexed here

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Oct 2026

Tauroursodeoxycholic acid ameliorates DSS-induced ulcerative colitis via regulating TLR4/NLRP3/pyroptosis axis and Keap1/Nrf2 pathway and restoring gut barrier function.

Tauroursodeoxycholic acid (TUDCA) is a naturally occurring endogenous hydrophilic bile acid with therapeutic potential for ulcerative colitis (UC). However, the potential mechanism of its anti-UC effect remains unclear. Hence, this study investigated the therapeutic efficiency of TUDCA on dextran sulfate sodium (DSS)-i...

Jing-Yuan Liu, Xin-He Wang, Jia-Ying Wang et al. · 0 citations
Open access Sep 2026

Berberine attenuates diabetic kidney injury via FOXO1/SP1-associated regulation of renal SGLT-2 expression

Berberine (BBR), a plant-derived isoquinoline alkaloid, has been reported to exert anti-hyperglycemic and renoprotective effects. However, the mechanism by which BBR regulates renal glucose transport under diabetic conditions remains unclear. Sodium-glucose cotransporter-2 (SGLT-2), mainly expressed in renal proximal t...

Jing-Jing Pan, Xin-He Wang, Xin-Yuan Han et al. · 0 citations

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