Author

Xin-Hua Xia

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Review Open access Aug 2026

ZIF-8 Nanodrug Delivery Systems: Construction Strategies, Functional Modifications, and Advances in Synergistic Tumor Therapy

Abstract Conventional chemotherapeutic agents are commonly hampered by off-target toxicity and multidrug resistance. Although nanoscale delivery systems can enhance targeting and controlled release, they are frequently constrained by insufficient drug-loading capacity. Zeolitic imidazolate framework-8 (ZIF-8), a metal–...

Rujia Xie, Wangxia Peng, Bozhi Zeng et al. · International Journal of Nan... · 0 citations

Review Open access Aug 2026

Nanosystem-Mediated Phototherapy (PDT/PTT) - Chemodynamic Therapy for Synergistic Antitumor Therapy: Strategies and Advances

This review constructs a refined mechanistic framework to elaborate the complementary mechanisms of PDT and PTT toward CDT in terms of reaction kinetics modulation, endogenous substrate replenishment, and tumor antioxidant defense inhibition, and the key bottlenecks hindering clinical translation.

Yuxuan Ma, Jie Gong, Zixuan Wu et al. · International Journal of Nan... · 0 citations