Sep 2026
AMPK/mTOR/ULK1-mediated cytotoxic autophagy synergizes with apoptosis to drive the anti-endometrial cancer efficacy of platinum nanoclusters.
BACKGROUND The clinical management of endometrial cancer (EC) is frequently hindered by the dose-limiting toxicities and acquired resistance associated with conventional cisplatin. This study aims to evaluate the therapeutic potential and precise intracellular mechanisms of a rationally engineered, highly biocompatible...
Meng-Jun Zhang, Jia-Lin Wang, H. Yue et al.
· Biomaterials Advances · 0 citations