Ultrasmall Cerium-EGCG Nanoparticles Ameliorate Sepsis via Macrophage Reprogramming and Ferroptosis Inhibition.
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection, in which oxidative stress, ferroptosis, and macrophage-driven immune dysregulation form a self-amplifying pathological cycle. Epigallocatechin gallate (EGCG), a natural polyphenol with antioxidant and immunomodulatory ac...