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Author

Xin-Kui Zhou

2 papers indexed here

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Sep 2026

Tmlhe deficiency induces neurodevelopmental dysfunction and synaptic excitatory/inhibitory imbalance linked to autism-like phenotypes in zebrafish.

Mutations in TMLHE, the initial enzyme for carnitine biosynthesis, are linked to autism spectrum disorder (ASD). However, the molecular mechanisms by which TMLHE defects contribute to neurodevelopmental abnormalities remain elusive. This study aimed to elucidate the role of tmlhe deficiency in vertebrate neural develop...

Ji-Tong Li, Xiao-Tong Zhao, Jie-Ru Wei et al. · 0 citations
Review Open access Aug 2026

Advances in organoids for personalized medicine: from technological development to clinical application

Organoids, three-dimensional cell culture models derived from patient tissues or stem cells, have emerged as a cutting-edge technology in personalized medicine, owing to their remarkable ability to closely recapitulate in vivo tissue architecture and function. This review provides a comprehensive overview of the techno...

Xin-Kui Zhou, Xing-Xue Yan, Zheng-Yang Zhang et al. · 0 citations

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