Pseudoheterins A-J, cyclic peptides from Pseudostellaria heterophylla and their potential as antidiabetic agents targeting α-glucosidase.
The LC-MS-guided phytochemical investigation of Pseudostellaria heterophylla, combined with the TLC analysis using ninhydrin as a detection reagent, led to the isolation of 21 cyclic peptides (1-21), including 10 undescribed ones (1-10). Their structures were elucidated via extensive spectroscopic analysis, LC-MS/MS, s...