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Open access Oct 2026

Large-scale plasma proteomic profiling enhances prediction of heart failure among hypertensive individuals: prospective insights from the UK Biobank

Background Hypertension is a major risk factor for heart failure (HF), but current clinical models have limited ability to identify high-risk individuals before overt disease. Plasma proteomics may capture early molecular changes and improve risk prediction. Methods We analysed 16,128 hypertensive UK Biobank Pharma Pro...

Mao-Hua Li, Xiao He, Sha-Sha Xiao et al. · 0 citations
Sep 2026

Comparative Evaluation of Five Obesity Indices for Cardiovascular and All-Cause Mortality Prediction in Prediabetes and Diabetes Population: A Prospective Cohort.

BACKGROUND In the US population, the association and predictive performance of obesity indices -- Body Mass Index (BMI), Body Shape Index (ABSI), Body Roundness Index (BRI), Waist Circumference (WC), and Waist-to-Height Ratio (WHtR) with mortality outcomes Cardiovascular Mortality (CVM) and All-Cause Mortality (ACM)) i...

De-Xiang Xia, Rui Li, Chang Shu et al. · 0 citations
Review Open access Sep 2026

Associations of per- and polyfluoroalkyl substances (PFAS) exposure with arterial stiffness: Evidence from NHANES 2011-2018.

The association between PFAS exposure and estimated pulse wave velocity was investigated via multiple statistical approaches, providing hypothesis-generating evidence for potential pathways and offer exploratory insights for prevention, while also highlighting the need for future studies employing more direct measures.

De-Xiang Xia, Rui Li, Chang Shu et al. · 0 citations

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