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Review Open access Sep 2026

The thermodynamic state map of biomolecular condensates

Biomolecular condensates spatiotemporally regulate cellular biochemistry through liquid-liquid phase separation. In this Perspective, we refine the Condensate Code as a testable thermodynamic state map that integrates continuous cellular inputs, intrinsic molecular grammar and boundary conditions to govern measurable m...

Yao-Yao Hou, Ling-Yun Jing, Kan Sun et al. · 0 citations
Open access Sep 2026

Single-cell transcriptomics reveals distinct microglial state remodeling associated with the (R)-nicotine/diosmetin combination and galantamine in LPS-challenged BV2 cells

It is indicated that the DR condition was associated with remodeling of LPS-challenged BV2 microglial-like states, attenuation of inflammatory programs, and increased neurotrophic outputs relative to LPS, without significantly reducing CCK-8-assessed metabolic activity.

Yi-Han Liu, Hao Yu, Jing-Bin Zhang et al. · 0 citations

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