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Review Open access Sep 2026

Histotripsy for Hepatocellular Carcinoma: From Bench to Bedside.

Hepatocellular carcinoma (HCC) remains a leading cause of cancer mortality, with limited curative options. Histotripsy is a noninvasive focused ultrasound ablation technique that destroys tumors through acoustic cavitation rather than heat-based methods, offering an alternative to radiofrequency and microwave ablation....

Su-Su Luo, Xing-Yu Wei, Xin-Yue Lu et al. · 0 citations
Sep 2026

Novel mTORC1 Booster LAPTM4A Potentiates Pathological Cardiac Hypertrophy.

BACKGROUND Excessive unnecessary protein accumulation in cardiomyocyte is a leading contributor for pathological cardiac hypertrophy and has been found closely regulated by the mTORC1 (mechanistic target of rapamycin complex 1) signaling and lysosome transmembrane proteins. However, the precise regulatory mechanism str...

Yu-Feng Hu, Wei Li, Man-Li Hu et al. · 0 citations

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