Gut Microbial Functional Ecology and Microbiota-Derived Metabolites in Rheumatoid Arthritis Autoimmunity
Highlights What are the main findings? RA-associated gut dysbiosis is characterized by stage-dependent functional ecological remodeling rather than taxonomic shifts alone. Microbiota-derived metabolites connect gut dysbiosis with epithelial barrier dysfunction, innate/adaptive immune imbalance, and joint inflammation....