Evaluation of Acute Pharmacokinetics and Liver Metabolic Response of L -Se-Methylselenocysteine in Mice Using UPLC-QqQ-MS/MS and Untargeted Metabolomics
L-Se-methylselenocysteine (L-SeMC) is a natural organic selenium compound with potential nutritional applications, but its acute disposition and metabolic responses remain incompletely characterized. Here, UPLC-QqQ-MS/MS was used to characterize L-SeMC pharmacokinetics and tissue distribution in H22 tumor-bearing mic...