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Author

Xin-Rui Fan

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Oct 2026

Hydrogel-based delivery of solanesol enhances Treg-astrocyte crosstalk and reduces scar formation following spinal cord injury.

Spinal cord injury (SCI) is a severe neurological condition that often leads to permanent disability, with glial scar formation serving as a key obstacle to functional recovery. In this study, we use transcriptomic profiling and molecular analyses to delineate the pathological signaling cascade involved in SCI. The TGF...

Shao-Song Sun, Xin-Rui Fan, Qiang-Qiang Guo et al. · 0 citations
Open access Sep 2026

Mechanistic Study on HSP90B1 Regulation of ClC-7 Ubiquitination to Restore Lysosomal Function in the Protection Proffered by DGMI Against Fluoride-Induced Cognitive Dysfunction.

BACKGROUND Fluorosis can induce cognitive dysfunction. The cognitive impairment caused by fluorosis is closely related to endoplasmic reticulum stress (ERS) and abnormal lysosomal acidification. However, the specific molecular mechanism is not known, and effective intervention strategies are lacking. Diterpene ginkgoli...

Rui Chen, Peng Xie, Xin-Rui Fan et al. · 0 citations

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