Author

Xin-Rui Wang

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Open access Oct 2026

A high-resolution spatial model of the primate gut microbiome defines niche-specific functions and host-adapted microbial metabolism

ABSTRACT The spatial organization of the gastrointestinal microbiome is shaped by strong physicochemical gradients along the gut, yet many region-associated microbial niches remain poorly resolved in humans. Here, we used the rhesus macaque (Macaca mulatta) as a spatially resolved primate model to profile 148 luminal a...

Shu-Wen Hou, Yue-Song Jiang, Deng-Wei Zhang et al. · Gut microbes · 0 citations

Review Open access Aug 2026

Cardiac microphysiological systems in cardiovascular research: Construction paradigms, maturation trajectories, and translational frontiers

Abstract Cardiovascular diseases remain the leading cause of global mortality, yet traditional preclinical models fail to accurately capture the physiological and genetic complexity of the human heart, hindering the development of targeted therapies. Cardiac microphysiological systems (cardiac MPS), including self‐orga...

Rong-Fang Xie, Haiyang Zhao, Yuqing Lei et al. · Bioengineering & Translation... · 0 citations