mFI and RAI are widely used in noncardiac surgical risk stratification, but they differ in content and data requirements. Because construct validity and outcome discrimination are distinct, we evaluated their prognostic discrimination for 30-day all-cause mortality without treating either instrument as a criterion-...
Xin-Rui Yin, Shi-Jia Du· Frontiers in Medicine· 0 citations
Background Agonistic anti-CD40 antibodies and related CD40 agonist biologics are being developed across multiple solid tumors using diverse biologic formats, delivery routes, and combination regimens. Safety is central to their clinical development but remains difficult to interpret because high-grade adverse events in...
Xin-Rui Yin, Shi-Jia Du· Frontiers in Immunology· 0 citations
Background Doomscrolling is persistent or repetitive engagement with predominantly negative, threatening, or distressing online information, often accompanied by difficulty disengaging. It overlaps with, but is not interchangeable with, problematic social media use, general negative-news exposure, or broader problemati...
Qi Li, Xin-Rui Yin· Frontiers in Psychology· 0 citations
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