Xin-Ruo Wu

Therapeutic Targeting of Tauopathies: From Druggable Biology to Precision Intervention.

Tauopathies encompass a heterogeneous group of neurodegenerative disorders characterized by the transition of tau from a microtubule-stabilizing protein into pathogenic, seed-competent species. Increasing evidence has redefined tau from a descriptive pathological hallmark to a pharmacologically actionable target across...