Jul 2026
Decoding the Functional Roles of Individual Components in mRNA Lipid Nanoparticles.
Lipid nanoparticles (LNPs) have represented a leading platform for mRNA delivery and therapeutics. While extensive studies have focused on optimizing ionizable lipids, the specific roles of helper lipids such as cholesterol, phospholipid, and polyethylene glycol lipid (PEG-lipid) remain relatively poorly understood. To...
Kexin Su, Zichuan Wang, Lu Shi et al.
· ACS Nano · 0 citations