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Xin-Tong Zhang

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Sep 2026

TrmD: A Promising Antibacterial Target and Its Small-Molecule Inhibitors

Bacterial tRNA-(N1G37) methyltransferase (TrmD), a member of the SPOUT superfamily, plays a pivotal role in catalyzing the methyl group transfer from S-adenosyl-l-methionine to the N1 position of G37 in the pathway of post-transcriptional modifications of bacterial tRNA. In response to the urgent global clinical need...

Zhi-Wei Meng, Dian-Fu Xia, Xin-Tong Zhang et al. · 0 citations

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