Xin-Xin Zhang

DMH glutamatergic and GABAergic neurons differentially regulate post-anesthesia sleep disturbance through CB1R signaling

Post-operative sleep disturbance affects more than 60% of surgical patients and impedes recovery. Although general anesthesia itself may profoundly remodel brain function and contribute to this pathology, the underlying neural mechanisms remain unclear. We previously identified the dorsomedial hypothalamus (DMH) as a k...