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Open access Oct 2026

Aziridination-Based Crosslinking Enables Site-Resolved Elucidation of Lipid Binding and Protein Conformational Changes

Lipid–protein interactions play critical roles in cellular function, yet their site-resolved characterization remains challenging due to the dynamic nature of lipid binding and the limited availability of chemoselective strategies for covalently capturing native lipid–protein contacts. Here, we introduce aziridinatio...

Chia-Lung Tsai, A. Tasnim, Zhen-Yu Xi et al. · 0 citations

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