DAPK1 overcomes vincristine resistance in osteosarcoma by inhibiting ER-phagy through the ERK signaling pathway.
Investigation of the potential role and molecular mechanisms of death-associated protein kinase 1 in vincristine (VCR) resistance in osteosarcoma concludes that DAPK1 enhances osteosarcoma cell sensitivity to VCR by inhibiting ERK-mediated ER-phagy, which may represent a promising therapeutic strategy to overcome drug...