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Author

Xinyi Wang

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Jul 2026

GNAS drives gastric cancer progression via pyrimidine metabolic reprogramming and immune-microenvironment remodeling

This work identified GNAS as a key metabolic hub gene, which is consistently upregulated in highly malignant subsets and strongly predictive of poor patient survival, and Targeting the GNAS-mediated metabolic-transcriptional axis exposes a novel therapeutic vulnerability.

Xin-Yi Wang, Heng Tian, Jiaju Wang et al. · 0 citations
Open access Aug 2026

Serum metabolic characteristics of interstitial lung disease: a potential link between endocrine aging and gut-derived metabolites

Untargeted metabolomics has revealed significant systemic metabolic dysregulation in ILD and the biomarkers and “metabolic-immune-endocrine” interaction patterns identified offer potential leads for early diagnosis and targeted treatment, which require validation in larger cohorts.

Lu Liu, Xin-Yi Wang, Jinling Xiao et al. · 0 citations

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