Open access
Sep 2026
Cycloastragenol extends lifespan and enhances stress resistance in Caenorhabditis elegans by inhibiting IIS pathway and activating p38 MAPK-mediated innate immunity.
Aging is a complex physiological process characterized by progressive functional decline, yet effective pharmacological interventions from medicine-food homologous sources remain limited. While Cycloastragenol (CAG), a bioactive triterpenoid from Astragalus membranaceus, is known for telomerase activation, its non-telo...
Chuan-Jiao Feng, Xiao-Yu Zhang, Tai-Li Zhao et al.
· European Journal of Pharmaco... · 0 citations