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Author

Xin-Yu Cui

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Sep 2026

Engineering Cellobiose Dehydrogenase for Enhanced Electron Transfer Efficiency and Minimized Oxygen Interference

Cellobiose dehydrogenase (CDH) is a typical biomass catalyst with significant potential for applications such as lignocellulose degradation, bioremediation, and bioelectrocatalysis. Its two-domain flavoheme structure enables the construction of direct electron transfer (DET)-based bioelectrochemical devices. However,...

Xin-Yu Cui, Hai-Yan Song, Yuan-Ming Wang et al. · 0 citations
Open access Sep 2026

A second-sphere variant of cytochrome P450 PbdA improves turnover and apparent coupling in veratrate oxidation

Efficient use of reducing equivalents is critical for productive turnover in cytochrome P450 redox enzymes, yet improving activity without compromising substrate affinity remains challenging. Here, we engineered the second-sphere region of PbdA, a cytochrome P450 from Rhodococcus jostii RHA1 that catalyzes veratrate ox...

Hai-Yan Song, Ze-Yang Li, An-Dong Li et al. · 0 citations

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