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Xin-Yu Zhou

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Open access Aug 2026

Feasibility, safety, and preliminary clinical efficacy of resting-state functional connectivity MRI-guided rTMS for adolescents with major depressive disorder: Protocol for a randomized, double-blind, three-arm, sham-controlled pilot trial

Background Major depressive disorder (MDD) is highly prevalent in adolescents, and a substantial proportion of patients show inadequate response or limited tolerability to first-line treatments such as selective serotonin reuptake inhibitors and cognitive behavioral therapy, highlighting the need for additional treatme...

Hongyi Chen, Dan-Yu Xu, Wen-Jing Wang et al. · 0 citations
Review Open access Jul 2026

Gut microbiota‐targeted interventions for depression in adolescents and young adults: Mechanisms, evidence strength and clinical strategies—A narrative review

Current evidence indicates that interventions targeting the MGB axis should be approached cautiously and considered only as adjunctive strategies for the treatment of depression in this population, and future work requires rigorously designed, strain‐ and protocol‐specific clinical trials with standardised procedures,...

Hanchen Hou, Yi-Nan Li, Wanting Tang et al. · 0 citations

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