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Xin-Yue Li

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Open access Aug 2026

Chemogenetic Manipulation of mPFC Neurons Counteracts Cognitive Deficits But Leaves Sleep Disturbances Unaffected in a Mouse Model of Chronic Intermittent Hypoxia

The mPFC is a critical hub for CIH-induced cognitive impairment, and its targeted inhibition can restore cognitive and synaptic function, however, sleep architecture disruptions are governed by distinct mechanisms, indicating a dissociation between CIH-mediated cognitive and sleep pathologies.

Guo Pei, Xin-Yue Li, Yuan-Yuan Wang et al. · 0 citations

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