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Author

Xinyue Liu

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Open access Sep 2026

Endolysin Kgh3 possesses anti-biofilm activity and affects Klebsiella pneumoniae biofilm formation through peptidoglycan degradation

Glycoside hydrolases contribute to both biofilm dispersion and the regulation of bacterial biofilm formation. The discovery of novel anti-biofilm glycoside hydrolases could enhance the understanding of biofilm formation and help to address the problem of chronic infections caused by biofilms. This study aimed to evalua...

Jia-Lin Li, Jing Zuo, Yan-Bin Chang et al. · 0 citations
Open access Aug 2026

hnRNPC facilitates coronavirus replication by directly binding the frameshift-stimulatory element of viral genomic RNA

HnRNPC is identified as a key host cofactor for coronaviruses and provides a novel target for broad-spectrum antiviral drug development and the small molecule Elbasvir directly binds hnRNPC, disrupting the interaction between hnRNPC and FSE RNA and inhibiting coronavirus replication by decreasing –1 PRF efficiency.

Jing-Chen Xu, Hong-Ying Li, Jian-Rui Li et al. · 0 citations
Review Sep 2026

Mitochondria-targeted natural products with potential for the treatment of mitochondria-related diseases.

This review systematically summarize the specific mitochondrial pathological phenotypes in various diseases and provides a comprehensive overview of natural products that correspond to these phenotypes, along with their mechanisms of action.

Xin-Yue Liu, Hu Li, Xuekai Wang et al. · 0 citations

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