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Xin-Yue Lu

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Review Open access Sep 2026

Histotripsy for Hepatocellular Carcinoma: From Bench to Bedside.

Hepatocellular carcinoma (HCC) remains a leading cause of cancer mortality, with limited curative options. Histotripsy is a noninvasive focused ultrasound ablation technique that destroys tumors through acoustic cavitation rather than heat-based methods, offering an alternative to radiofrequency and microwave ablation....

Su-Su Luo, Xing-Yu Wei, Xin-Yue Lu et al. · 0 citations
Review Open access Sep 2026

From metabolic antagonism to homeostatic restoration: rewiring hepatic stellate cell bioenergetics for liver fibrosis reversal

Emerging evidence has redefined metabolic reprogramming in hepatic stellate cells (HSCs) from a mere energy-supporting process to an active driver of liver fibrosis. Unlike conventional descriptions that focus on isolated pathway alterations, recent advances show that activated HSCs coordinate a multi-layered metabolic...

Xin-Yue Lu, Zi-Long Li · 0 citations

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