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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Xin Zhang

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Open access Sep 2026

From Coordination Chemistry to Immune Modulation: Rational Design of Next‐Generation Mn 2+ ‐Based Immunomodulators

Mn 2+ has emerged as a potent immunostimulatory modulator capable of activating cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) and other innate immune signaling pathways. Consequently, Mn 2+ induces type I interferon responses, and promotes robust antitumor and antiviral immunity. Recent...

Xin Zhang, Hélder A. Santos, Bing Xia · 0 citations

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