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Open access Sep 2026

The DNA/RNA Helicase SETX Maintains R‐Loop Homeostasis to Promote Chemoresistance in Ovarian Cancer

ABSTRACT Ovarian cancer is a lethal malignancy that frequently develops resistance to platinum‐based chemotherapies. Elucidating the genes that regulate DNA damage repair could lead to more effective treatments for ovarian cancer. Senataxin (SETX), an RNA–DNA helicase, maintains R‐loop homeostasis to ensure replication...

Zi-Wei Hu, Tu-Nan Xu, Zi-Ying Wang et al. · 0 citations
Open access Sep 2026

Global, regional, and national burden of ovarian cancer from 1990 to 2021

Ovarian cancer is one of the most lethal gynecological malignancies globally, with significant variations in incidence, prevalence, and outcomes across regions and population subgroups. This study systematically evaluates the global, regional, and national burden of ovarian cancer from 1990 to 2021, utilizing data from...

Chao-Kang Huang, Xin Zheng, Ya-Jing Zhang et al. · 0 citations

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