Open access
Aug 2026
LRRN4 Upregulates the IL23A-JAK2-STAT3 Signaling Axis and Drives Colorectal Cancer Metastasis.
In colorectal cancer (CRC), metastasis drives fatalities, necessitating the discovery of therapeutic targets modulating its progression. Though the secreted protein-coding gene leucine-rich repeat neuronal 4 (LRRN4) was shown to be highly overexpressed in CRC and linked to decreased survival in the analysis of TCGA-CRC...
Jia-Tian Lin, Shasha Min, Ze-Song Li et al.
· Molecular Carcinogenesis · 0 citations