Jul 2026
GATA6-mediated transcriptional activation and METTL3/IGF2BP2-dependent post-transcriptional stabilization upregulate CDC20 to promote the malignant progression of colorectal cancer and immune escape
CDC20, upregulated transcriptionally by GATA6 and post-transcriptionally by METTL3, drove CRC progression, angiogenesis, and immune evasion and reversed the inhibitory effects of METTL3 knockdown on CRC cell malignancy and immune escape.
Yuyu Wang, Xinfei Wang, Yongsheng Chang et al.
· Human Cell · 0 citations