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Author

Xing-Bing Wang

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Review Aug 2026

CAR-T Cell Therapy-Associated Coagulopathy: From Immunothrombotic Storm Mechanisms to Precision Management Strategies.

Chimeric antigen receptor T-cell (CAR-T) therapy has transformed the management of relapsed or refractory hematologic malignancies, yet its benefit is constrained by immune-mediated vascular toxicities. CAR-T-associated coagulopathy (CARAC) is an under-recognized, potentially fatal syndrome driven by endothelial activa...

Buyi Su, Xing-Bing Wang · 0 citations
Open access Sep 2026

Efficacy and Safety of CAR‐T Cell Therapy in Relapsed/Refractory B‐Cell Acute Lymphoblastic Leukemia With Central Nervous System Involvement

Central nervous system (CNS) involvement in B‐cell acute lymphoblastic leukemia (B‐ALL) is associated with relapse, treatment refractoriness, and poor prognosis. Although chimeric antigen receptor (CAR) T cell therapy has demonstrated remarkable efficacy in relapsed/refractory (R/R) B‐ALL, its efficacy and safety in CN...

Yang-Hong Yu, Hui Xu, Lei Xue et al. · 0 citations
Open access Jul 2026

Ultralow-Dose Interleukin 10-Expressing Chimeric Antigen Receptor T Cells in Relapsed/Refractory Diffuse Large B-Cell Lymphoma: A Nonrandomized Clinical Trial.

The results of this nonrandomized clinical trial suggest that ultralow-dose META 10-19 demonstrated promising antitumor activity and a manageable safety profile in patients with R/R DLBCL.

Yong-Xian Hu, Ming-Ming Zhang, M. Gao et al. · 1 citation

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