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Xing Chang

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Review Open access Sep 2026

Natural Products Modulate Plaque Macrophage Functional Programs in Atherosclerosis

Abstract Atherosclerosis is a chronic inflammatory and immunometabolic disease in which plaque macrophages integrate lipid-derived danger signals, metabolic stress and cell-death cues to shape foam-cell formation, necrotic-core expansion, fibrous-cap integrity and plaque vulnerability. Moving beyond the conventional M1...

Kai Yang, Shi-Yi Tao, Rui-Kang Liu et al. · 0 citations

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