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Xing-Ding Zhang

2 papers indexed here

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Open access Sep 2026

PTTG1-driven self-amplifying loop with SP1 and ENO1 promotes IRF4-mediated myeloma progression and bone destruction

Multiple myeloma (MM) is a neoplastic disorder of plasma cells within the hematopoietic system and is characterized by osteolytic lesions. Despite significant advances, the molecular underpinnings of myeloma and its associated bone pathologies remain elusive, and there is an unmet need for effective targeted therap...

Rui Liu, Ya-Zhu Huang, Zhi-Hong Fang et al. · 0 citations
Open access Sep 2026

The NSDHL/c-Myc/PKM2 Axis Drives Glycolytic Reprogramming and Tumor Growth in Multiple Myeloma

Multiple myeloma (MM) remains largely incurable because of its complex biology and frequent disease relapse. Metabolic reprogramming is increasingly recognized as a critical contributor to MM progression. NAD (P)-dependent steroid dehydrogenase-like protein (NSDHL) has been highlighted as an unfavorable metabolism-rela...

Can Yue, Bei-Hui Huang, Lin Qi et al. · 0 citations

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