Open access
Aug 2026
Immune niche composed of C1Q+ macrophages/SFRP2+ CAFs/CD8+ T cells drives immunotherapy response in HER2-positive gastric cancer
It is shown by spatial transcriptomics and single-cell RNA sequencing that HER2 positivity associates with a favourable immune microenvironment that also determines their better response to immunotherapy.
Yu-Han Liao, Xin-Hua Chen, Hai-Yun Chen et al.
· Nature Communications · 0 citations