Xing-Jian Luo

Protein Phase Separation and Regulatory Mechanisms of Transcriptional Programming in Tumor Microenvironment in Stress Response

Malignant tumor evolution is governed by its symbiotic relationship with the tumor microenvironment, which features steep oxygen and acidity gradients that drive malignant progression. Traditional biochemical frameworks fail to adequately explain the rapid, coordinated genomic alterations under such stresses. This revi...