Mxd1-mediated transcriptional repression of FTO induces NLRP3-dependent pyroptosis in retinal microglia.
Pyroptosis of retinal microglial cells represents a key pathological event in degenerative disorders of the retina, yet the molecular drivers of this process remain incompletely understood. This study investigates the molecular drivers of retinal microglial pyroptosis using primary murine retinal microglial cells and H...