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Author

Xingyu Liu

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Jul 2026

PSGS-Drug: Generation-Time Dual-Pocket Guidance for Non-Symmetric Dual-Target Molecular Design

Docking scores, operational dual-hit labels, and residue-level contact analyses are interpreted as fixed-protocol computational prioritization signals that support candidate selection for this pathway-linked dual-context hypothesis.

Yuchen Zhou, Tianhe Gu, Liang Tian et al. · 0 citations
Open access Aug 2026

Identification of YL064 as a novel inhibitor of ATXN3 to suppress tumor growth and metastasis by promoting degradation of oncogenic substrates

YL064 is established as a promising ATXN3 inhibitor that targets the ubiquitin-proteasome pathway to exert anti-tumor effects, highlighting its potential as a novel therapeutic agent for ATXN3-driven cancers.

Zhenge Zhang, Wenhui Bai, Yayue Tan et al. · 0 citations

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